Endocrine Abstracts

Context: The biological diagnosis of adrenal disorders is currently based on the quantitation of serum steroids using automated immunoassays. These direct assays often lack the required accuracy and precision and interlaboratory surveys show that performance characteristics of MSMS are far better than those of automated immunoassays.Method: After liquid chromatography of serum extracts, steroids were quantified on Waters QuattroPremier mass-spectrometer ...